Description of breast cancer risk program
Fairfax Radiological Consultants, P.C. provides this informational tool courtesy of the
(IBIS) International Breast Cancer Intervention Study

The program assumes that there is a gene predisposing to breast cancer in addition to the BRCA genes. The woman's family history is used to calculate the likelihood of her carrying an adverse gene, which in turn affects her likelihood of developing breast cancer. The risks of developing breast cancer for the general population were taken from the national data rates for breast cancer in 1994. These rates are quite high and are higher than the risks described in most papers, however this may be because of the increase in breast cancer over the centuries.

The risk from family history (caused by the adverse genes) is modelled to fit the results in "Familial Breast and Ovarian Cancer: A Swedish Population-based Register Study, Anderson H et al., American Journal of Epidemiology 2000, 152: 1154-1163".

download IBIS Genetic Breast Cancer Predisposition Tool

Contact Details:

Prof. Jack Cuzick
Cancer Research UK Centre of Epidemiology, Mathematics and Statistics,
Wolfson Institute of Preventive Medicine,
Charterhouse Square,
London
EC1M 6BQ

email: riskevaluator@ems-trials.org